Objectives. The aimof this study was to evaluate if xanthine oxidase andmyeloperoxidase levels quantitationmethodmay alternate\r\nroutine culture method, which takes more time in the diagnosis of urinary tract infections. Material and Methods. Five hundred\r\nand forty-nine outpatients who had admitted to Clinic Microbiology Laboratory were included in the study.The microorganisms\r\nwere identified by using VITEK System. The urine specimens that were negative from the quantitative urine culture were used as\r\ncontrols. The activities of MPO and XO in spot urine were measured by spectrophotometric method. Results.Through the urine\r\ncultures, 167 bacteria were isolated from163 urine specimens; 386 cultures yielded no bacterial growth. E. coli was the most frequent\r\npathogen. In infection with E. coli both XO andMPO levels were increased the most. The sensitivity, specificity, positive predictive\r\nvalue, and negative predictive value for XO were 100%, 100%, 100%, and 100%, respectively.These values for MPO were 87%, 100%,\r\n100%, and 94%, respectively. Conclusion. These data obtained suggest that urine XO and MPO levels may be new markers in the\r\nearly detection of UTI.
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